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The Science

The research behind
every decision we make

Heat therapy is one of the most powerful tools for men's health. But it comes with tradeoffs most guys don't know about — until now.

01

Why Sauna Is Non-Negotiable

Regular sauna use isn't a trend — it's one of the most well-studied wellness practices on the planet. The landmark Kuopio Ischemic Heart Disease study followed 2,315 men for over 20 years and the results changed how we think about heat therapy.

63%
Reduction in sudden cardiac death
4–7 sessions/week
50%
Reduction in fatal cardiovascular disease
4–7 sessions/week
40%
Reduction in all-cause mortality
4–7 sessions/week
66%
Lower risk of dementia
4–7 sessions/week
Source: Laukkanen et al., JAMA Internal Medicine, 2015 · Age and Ageing, 2017

Even moderate use delivered powerful results — 2–3 sessions per week produced a 22% lower risk of sudden cardiac death. Spending 19+ minutes per session cut risk by 52%. A randomized clinical trial also found that a single whole-body hyperthermia session produced significant antidepressant effects within one week that lasted through week six.

32%
Increase in run time to exhaustion
Athletic Performance · Scoon et al., 2007
8 mmHg
Additional BP reduction beyond exercise alone
Exercise + Sauna · Lee et al., 2022
Sauna

200°F. 20 minutes. 7 days a week.

Bryan Johnson's Protocol

Real-World Proof at the Extreme

Bryan Johnson — the tech entrepreneur spending millions on age reversal — uses a dry Finnish sauna at 200°F for 20 minutes, 7 days per week. His self-tracked data across 48 sessions represents one of the most detailed personal case studies on sauna benefits ever documented.

25–50%
Arterial flexibility improvement
Over 48 sessions
38%
Heart rate variability improvement
Over 48 sessions
~20 mmHg
Blood pressure improvement
Over 48 sessions

How His Results Progressed Over Time

Sessions 1–15
Dramatic Toxin Elimination
Lab work revealed dramatic reductions in seven environmental toxins. Three compounds — MEP, MEHP, and Perchlorate — went from abnormally high levels to completely undetectable. Johnson called it "the best toxins result I'd ever received."
Sessions 15–23
Heavy Metal Clearance
Arsenic, cadmium, and lead — which had been elevated following LA wildfire exposure — dropped to undetectable levels. An 85% reduction in measured microplastics was reported across tested samples.
Sessions 23–48
Cardiovascular Transformation
Arterial flexibility improved 25–50%, HRV improved 38%, and blood pressure improved approximately 20 mmHg. These gains compounded over the full protocol, demonstrating that consistent sauna use delivers cumulative cardiovascular benefits.

Toxin Reduction Results After 15 Sessions

100%
MEP (Phthalate)
Endocrine disruptor
Undetectable
100%
MEHP (Phthalate)
Endocrine disruptor
Undetectable
100%
Perchlorate
Industrial chemical
Undetectable
65%
2,4-D
Herbicide
56%
Naphthalene
VOC metabolite
56%
HEMA
VOC metabolite

Many of the same endocrine disruptors found in synthetic underwear — phthalates, VOCs, and industrial chemicals — are the exact compounds Johnson was eliminating through sweat. The sauna doesn't just benefit your heart. It actively helps clear the harmful substances that accumulate from daily exposure to synthetic materials, contaminated environments, and modern life.

Source: blueprint.bryanjohnson.com

02

What Heat Does to Your Sperm

Here's the part most wellness influencers skip over. The same heat that benefits your heart, muscles, and mind can temporarily impair your reproductive health.

Your testes sit outside the body for a reason — they need to stay 3.5–5.5°F cooler than core temperature for healthy sperm production. During a sauna session, scrotal temperature rises from ~91°F to ~99.5°F within 10 minutes — eliminating the thermal difference your body needs.

Scrotal Temperature During Sauna Use
Optimal
~91°F
After 10 min
~99.5°F

A clinical study had healthy men use a Finnish sauna twice per week for three months. The results: significant declines in sperm count, motility, and DNA integrity. Mitochondrial function declined. Heat shock and hypoxia genes were activated.

Source: Garolla et al., Human Reproduction, 2013

A meta-analysis of 9 studies (356 men) confirmed large negative effects across every sperm parameter — motility, morphology, concentration, count, and volume were all significantly reduced.

Infertile men who stopped hot tub use saw a mean increase in total motile sperm count of 491%

Shefi et al., International Brazilian Journal of Urology, 2007

The good news: these effects are reversible. In most studies, sperm parameters returned to baseline within 3–6 months after heat exposure stopped. But for men actively trying to conceive — or planning to in the near future — that timeline matters.

The current advice from fertility experts is blunt: avoid saunas if you're trying to conceive. But that forces an impossible choice — give up the cardiovascular, recovery, and mental health benefits of heat therapy, or risk your reproductive health. We built QUOR so you don't have to choose.

QUOR Product

Same principle. Engineered into your gear.

Bryan Johnson confirmed the solution works. With ice protection during every session:

+31%
Fertility markers improved
With ice protection
−50%
Markers dropped when he stopped
Without protection

His protected levels reached 6x the clinical threshold for healthy sperm — outperforming 99.6% of tested men, including those under 25. When he stopped using ice protection, those same markers dropped by 50%, confirming that heat without protection directly impairs reproductive health.

This is the exact problem QUOR is engineered to solve — and Johnson's real-world data proves the principle works.

Andrew Havill, Co-Founder and CEO of QUOR™

03

The Hidden Danger of Synthetic Materials

Most men's underwear — including what most guys wear in the sauna — is made from synthetic fabrics like polyester, nylon, and spandex. The research on what these materials do to male reproductive health is alarming.

In clinical studies, polyester generated electrostatic charges of 326–395 V/cm² on scrotal skin — while cotton generated zero charge and zero negative effects on sperm parameters

Shafik, Contraception, 1992

In a landmark study, 14 healthy men wore a polyester scrotal sling for 12 months. The synthetic material generated significant electrostatic interference that severely impaired sperm production. After removal, sperm parameters returned to normal and all couples seeking pregnancy conceived. In animal studies, polyester caused significant declines in sperm count, motility, and sexual function — while cotton and wool groups showed no negative changes whatsoever, identical to unwearing controls.

Synthetic Fabrics

  • 326–395 V/cm² electrostatic charge on scrotal skin
  • Microplastics found in 100% of human testes examined
  • Antimony leaches from polyester into sweat at high temperatures
  • PFAS absorption increases up to 3,252x with sweat
  • VOC emissions increase significantly with temperature
  • Significant impairment of sperm production in clinical studies

Natural Fibers (Cotton)

  • Zero electrostatic charge generated
  • Zero negative effects on sperm parameters
  • No microplastic shedding
  • No chemical leaching during heat exposure
  • No endocrine disruption
  • Identical results to unwearing controls in studies

A 2024 study found microplastics in 100% of human testes examined — 12 different polymer types. PVC and PET (polyester) levels negatively correlated with testis weight and sperm count. Antimony — present in 80–85% of all polyester — leaches from synthetic fabrics into sweat, with release increasing at higher temperatures. PFAS ("forever chemicals") were found in nearly 88% of textile samples tested, with sweat increasing absorption by up to 3,252-fold compared to dry contact.

In a sauna — where you're sweating continuously at extreme temperatures — synthetic fabrics become a delivery system for endocrine disruptors directly onto your most sensitive skin.

Natural Materials

Clean materials. Zero compromise.

Section 04

How QUOR Is Tackling This

Integrated Cooling Insert

A purpose-built pocket holds a cooling insert that maintains optimal scrotal temperature during heat exposure. The same principle Bryan Johnson uses — engineered into your gear.

Dual-Layer Natural Fiber

95% bamboo / 5% elastane body for thermoregulation and antimicrobial protection. 100% organic cotton groin — the material proven to generate zero electrostatic charge.

No Synthetics Where It Matters

No polyester, nylon, or synthetic blends in direct groin contact. No microplastics. No endocrine disruptors. No electrostatic fields. Just clean, certified materials.

OEKO-TEX & GOTS Certified

Tested against 1,000+ harmful substances. Strict organic sourcing. Limits on phthalates, BPA, PFAS, formaldehyde, heavy metals, and banned azo dyes.

We're not here to scare you
away from the sauna.

We're here to make sure you can keep going.

Shop the System

References

1. Laukkanen T et al. "Association Between Sauna Bathing and Fatal Cardiovascular and All-Cause Mortality Events." JAMA Internal Medicine, 2015.
2. Laukkanen T et al. "Sauna bathing is inversely associated with dementia and Alzheimer's disease." Age and Ageing, 2017.
3. Janssen CW et al. "Whole-Body Hyperthermia for the Treatment of Major Depressive Disorder." JAMA Psychiatry, 2016.
4. Scoon GSM et al. "Effect of post-exercise sauna bathing on endurance performance." J Science and Medicine in Sport, 2007.
5. Lee E et al. "Effects of regular sauna bathing in conjunction with exercise on cardiovascular function." Am J Physiology, 2022.
6. Zaccardi F et al. "Sauna Bathing and Incident Hypertension." Am J Hypertension, 2017.
7. Garolla A et al. "Seminal and molecular evidence that sauna exposure affects human spermatogenesis." Human Reproduction, 2013.
8. Hoang-Thi AP et al. "Impact of High Ambient Temperature on Human Sperm Parameters." Iranian J Public Health, 2022.
9. Shefi S et al. "Wet heat exposure: a potentially reversible cause of low semen quality." Int Brazilian J Urology, 2007.
10. Shafik A. "Contraceptive efficacy of polyester-induced azoospermia in normal men." Contraception, 1992.
11. Shafik A. "Effect of different types of textile fabric on spermatogenesis." Urological Research, 1993.
12. Mínguez-Alarcón L et al. "Type of underwear worn and markers of testicular function." Human Reproduction, 2018.
13. Hu CJ et al. "Microplastics detected in human and canine testes." Toxicological Sciences, 2024.
14. Biver M et al. "Antimony release from polyester textiles by artificial sweat." Regulatory Tox and Pharmacology, 2021.
15. Li K et al. "Sweat-amplified dermal transfer of PFAS from textiles." Science of the Total Environment, 2025.

The information provided on this page is for educational and informational purposes only and is not intended as medical advice. QUOR Wellness Inc. does not diagnose, treat, cure, or prevent any disease. The research cited reflects published peer-reviewed studies and publicly available data; individual results may vary. Always consult a qualified healthcare professional before making changes to your health routine, particularly regarding fertility, heat exposure, or any medical condition. QUOR products are wellness accessories and are not FDA-approved medical devices.